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4363.0.55.001 - Australian Health Survey: Users' Guide, 2011-13  
Latest ISSUE Released at 11:30 AM (CANBERRA TIME) 11/12/2013   
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Contents >> Biomedical Measures

BIOMEDICAL MEASURES

The Australian Health Survey (AHS) biomedical measures component is a new collection, which forms the National Health Measures Survey (NHMS). The NHMS has been made possible by additional funding from the Australian Government Department of Health and Ageing as well as the National Heart Foundation of Australia. The NHMS measured specific biomarkers for chronic disease and nutrition status, derived from tests on blood and urine samples from volunteering participants selected in the AHS.

All people aged 5 years and over who participated in either the National Health Survey (NHS) or the National Nutrition and Physical Activity Survey (NNPAS) were invited to participate in the NHMS, which took place throughout Australia, from March 2011 to September 2012. Children aged 5–11 years were asked to provide a urine sample only, whereas people aged 12 years and over were asked to provide both a blood and urine sample, which were then analysed for specific biomarkers. In the NHMS, a biomarker generally refers to a measured characteristic, which may be used to indicate a health risk factor or condition.

The biomarkers included were selected based on the key policy objectives set out by the Department of Health and Ageing.1 A number of other tests were considered and discussed by the Department's biomedical expert group, and specific tests to measure chronic disease and nutrition status were selected based on the operational requirements and funding of the program, and the feasibility for a population health survey.

Ethics approval for the NHMS was granted by the Australian Government Department of Health and Ageing Departmental Ethics Committee (DEC) in February 2011.

The 2011–12 NHMS collected information about:

  • chronic disease biomarkers, including tests for diabetes, cholesterol, triglycerides, kidney disease and liver function
  • nutrient biomarkers, including tests for iron, folate, iodine and vitamin D levels.

Estimates of the prevalence of chronic disease risk factors such as cardiovascular disease, diabetes and chronic kidney disease have been collected in the NHS and NNPAS; and dietary behaviour and physical activity estimates have been collected in the NNPAS. These surveys are a good source of self reported data. Whilst self reported estimates are a good source of data, they may underestimate the true prevalence of these diseases. The NHMS data can be used together with the self reported data collected in the NHS and NNPAS to provide an objective measure of Australia's nutritional status and prevalence of chronic disease, whilst also providing data on undiagnosed cases of disease.

This chapter provides information about the following chronic disease and nutrient biomarkers that were collected for the National Health Measures Survey (NHMS).
SUMMARY OF CHRONIC DISEASE BIOMARKERS

AgeTest typeFasting

Cardiovascular disease biomarkers

Total cholesterol12+BloodNo
High Density Lipoprotein (HDL) cholesterol12+BloodNo
Low Density Lipoprotein (LDL) cholesterol12+BloodYes
Triglycerides12+BloodYes
Apolipoprotein B (Apo B)12+BloodNo

Diabetes biomarkers
Fasting plasma glucose12+BloodYes
Glycated Haemoglobin (HbA1c)12+BloodNo

Kidney disease biomarkers

Albumin creatinine ratio (ACR)5+UrineNo
Estimated glomerular filtration rate (eGFR)18+BloodNo

Liver function biomarkers

Alanine aminotransferase (ALT)12+BloodNo
Gamma glutamyl transferase (GGT)12+BloodNo

Tobacco use

Cotinine12+BloodNo


SUMMARY OF NUTRIENT BIOMARKERS


AgeTest typeFasting

Folate & Vitamin B12

Serum folate12+BloodNo
Red cell folate (RCF)12+BloodNo
Serum vitamin B1212+BloodNo

Iron

Serum ferritin12+BloodNo
Inflammation marker (C-reactive Protein (CRP))12+BloodNo
Soluble transferrin receptor (sTfR)12+BloodNo
Haemoglobin (Hb)12+BloodNo

Vitamin D

Serum 25-hydroxyvitamin D [25(OH)D]12+BloodNo

Iodine

Iodine concentration5+UrineNo

Sodium

Sodium concentration5+UrineNo

Potassium

Potassium concentration5+UrineNo


More information regarding the biomedical tests can be found in the relevant subsections.

ENDNOTES

1 Department of Health and Ageing 2011, Biomedical Component of the Australian Health Survey: Public health objectives, <http://www.health.gov.au/internet/main/publishing.nsf/Content/health-pubhlth-strateg-food-monitoring.htm/$File/Biomedical%20component%20AHS-public%20health%20objectives.pdf>, Last accessed 13/11/2013.


This section contains the following subsection :
      Biomedical comorbidity
      Cardiovascular disease (CVD) biomarkers
      Diabetes biomarkers
      Chronic Kidney Disease (CKD) biomarkers
      Liver function biomarkers
      Cotinine biomarker
      Folate and vitamin B12 biomarkers
      Iron biomarkers
      Iodine biomarker
      Vitamin D biomarker
      Sodium biomarker
      Potassium biomarker
      Blood and urine collection, and laboratory analysis

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